Eric Nybo, PhD

Eric Nybo, PhD

Associate Professor of Medicinal Chemistry
Pharmaceutical Science
Phone: (231) 591-2236
Email: [email protected]

Education

• PhD, University of Kentucky, College of Pharmacy, Pharmaceutical Sciences, Natural Products Biosynthesis
• BA, Transylvania University, Biology and Classics

Graduate/Post-Graduate Training

• Fellowship, Postdoctoral Fellowship, University of Kentucky College of Pharmacy, Lexington, KY

Biography

Dr. Nybo grew up in Knoxville, TN until he left for Lexington, KY where he completed his undergraduate and graduate studies. He graduated with a B.A. in Biology and Classics from Transylvania University in 2006. He went onto complete his Ph.D. in Pharmaceutical Sciences from the University of Kentucky in 2011.

He conducted a postdoctoral fellowship in the University of Kentucky Department of Plant and Soil Sciences from 2011-2014 in microbial biofuels research. In 2013, Dr. Nybo was invited back to Transylvania University as a Visiting Assistant Professor of General Chemistry.

Dr. Nybo joined the faculty of the College of Pharmacy, Department of Pharmaceutical Sciences in July 2014.

Publications and Intellectual Contributions

• Journal Article
  Nguyen, J. T., Brown, K. V., Riebschleger, K. K., Gorgijevska, N. M., Nybo, E. (2021). "A BioBricks® toolbox for multiplexed metabolic engineering of central carbon metabolism in the tetracenomycin pathway," Biotechnology Journal. Hoboken, New Jersey: Wiley. https://onlinelibrary.wiley.com/doi/10.1002/biot.202100371
• Journal Article
  Ossai, J., Nybo, S. E., Khatabi, B., Kharel, M. K. (2021). "Renewed interests in the discovery of bioactive actinomycetes metabolites driven by emerging technologies," Journal of Applied Microbiology. Hoboken, New Jersey: Wiley. https://sfamjournals.onlinelibrary.wiley.com/doi/10.1111/jam.15225
• Journal Article
  Wandi, B. N., Brown, K., Metsa-Ketela, M., Nybo, E. (2020). "Pathway engineering of anthracyclines: Blazing trails in natural product glycodiversification," Journal of Organic Chemistry. The American Chemical Society. https://doi.org/10.1021/acs.joc.0c01863
• Journal Article
  Nybo, E., Sahr, M., Young, M., Axford, K. L., Sohn, M., Lyons, M., Klepser, M. E. (2020). "Design of a large scale escape room for first-year pharmacy student orientation," Currents in Pharmacy Teaching and Learning. Amsterdam, Netherlands: Elsevier. https://www.sciencedirect.com/science/article/pii/S1877129720302173
• Journal Article
  Pontefract, B., Ho, H. T., Crain, A., Kharel, M. K., Nybo, E. (2020). "Drugs for Gram-Negative Bugs from 2010 - 2019: A decade in review," Open Forum Infectious Diseases. Oxford, England: Oxford University Press. https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofaa276/5867191
• Blog Article
  Nybo, E., VanLangen, K. M., Bright, D. R. (2020). "Social Distancing: Transitioning integrated pharmacotherapy coursework from face-to-face delivery to distance learning," Pulses. Currents in Pharmacy Teaching and Learning Scholarly Blog. https://cptlpulses.com/2020/04/07/social-distancing-lessons/
• Cited Research
  Brown, K., Nybo, E. (2020). "Next-generation sequencing of pIJ101-based Streptomyces-E. coli shuttle vectors," bioRxiv. https://www.biorxiv.org/content/10.1101/2020.02.26.966358v1
• Journal Article
  Nybo, E., Klepser, M. E., Klepser, S. (2020). "Design of a disaster preparedness escape room for first and second year pharmacy students," Currents in Pharmacy Teaching and Learning. 12 (7). pp. 716-723. Amsterdam, Netherlands: Elsevier. https://www.sciencedirect.com/science/article/abs/pii/S1877129720300630
• Cited Research
  Maki, K., Brown, K., Coe, M., Sohn, M., Nybo, E. (2019). "Design of experiments and metabolic engineering approach to enhance nogalamycin production in Streptomyces nogalater," bioRxiv. https://www.biorxiv.org/content/10.1101/804179v1
• Journal Article
  Nybo, E., Lamberts, J. (2019). "Integrated use of LC/MS/MS and LC/QTOF/MS targeted metabolomics with automated label-free microscopy for quantification of purine metabolites in cultured mammalian cells," Purinergic Signaling. pp. 1-9. Rotterdam, Netherlands: Springer Netherlands. https://link.springer.com/article/10.1007%2Fs11302-018-9643-2#citeas

Presentations

• Oral Presentation
  Nguyen, J. T. (Author & Presenter), Riebschleger, K. R. (Author), Brown, K. V. (Author), Nybo, E. (Author), West Michigan Regional Undergraduate Science Research Conference (WMRUGS), "BIOPOLYMER-ARO/CYC: BioBricks® Polyketide metabolic engineering of aromatases and cyclases," Van Andel Institute, Grand Rapids, MI, (November 12, 2021).
• Poster
  Hunt, S. (Author & Presenter), Nguyen, J. (Author), Hecht, J. (Author), Schwartz, N. (Author), Nybo, E. (Author), West Michigan Regional Undergraduate Science Research Conference (WMRUGS), "BIOPOLYMER: BIOBricks® POLYketide Metabolic EngineeRing of minimal polyketide synthases," Van Andel Institute, Grand Rapids, MI, (November 12, 2021).
• Poster
  Hecht, J. (Author & Presenter), Nguyen, J. (Author), Schwartz, N. (Author), Brown, K. V. (Author), Nybo, E. (Author), West Michigan Regional Undergraduate Science Research Conference (WMRUGS), "Engineering of diverse post-PKS enzymatic steps in anthracyclinone biosynthesis," Van Andel Institute, Grand Rapids, MI, (November 12, 2021).
• Poster
  Schwartz, N. (Author), Hecht, J. (Author & Presenter), Nguyen, J. (Author), Nybo, E. (Author), West Michigan Regional Undergraduate Science Research Conference (WMRUGS), "Engineering of late-stage polyketide biosynthesis steps in the nogalonic acid pathway," Van Andel Institute, Grand Rapids, MI, (November 12, 2021).
• Poster
  Brown, K. V. (Author & Presenter), Nguyen, J. T. (Author), Gorgijevska, N. (Author), Nybo, E. (Author), West Michigan Regional Undergraduate Science Research Conference (WMRUGS), "Metabolic engineering of new D-fucosyl and D-rhodinosyl tetracenomycins," Van Andel Institute, Grand Rapids, MI, (November 12, 2021).
• Oral Presentation
  Nybo, E. (Author), Department of Pharmaceutical Sciences Seminar, "Combinatorial biosynthesis of new tetracenomycins," University of Maryland Eastern Shores, Online, (November 11, 2021).
• Oral Presentation
  Nybo, E. (Author & Presenter), Nguyen, J. (Author), Riebschleger, K. (Author), Brown, K. V. (Author), Fall 2021: Resilience of Chemistry - American Chemical Society National Meeting, "Biopolymer: Biobricks polyketide metabolic engineering of minimal polyketide synthases in Streptomyces coelicolor," American Chemical Society, Atlanta, GA, (August 24, 2021).
• Poster
  Nguyen, J. T. (Author & Presenter), Riebschleger, K. R. (Author), Brown, K. V. (Author), Nybo, E. (Author), Fall 2021: Resilience of Chemistry - American Chemical Society National Meeting, "BIOPOLYMER-ARO/CYC: BioBricks® Polyketide metabolic engineering of aromatases and cyclases," The American Chemical Society, Atlanta, GA, (August 22, 2021).
• Poster
  Brown, K. V. (Author & Presenter), Nguyen, J. T. (Author), Gorgijevska, N. (Author), Nybo, E. (Author), Fall 2021: Resilience of Chemistry - American Chemical Society National Meeting, "Metabolic engineering of new D-fucosyl and D-rhodinosyl tetracenomycins," The American Chemical Society, Atlanta, GA, (August 22, 2021).
• Poster
  Brown, K. V. (Author), Riebschleger, K. (Author), Gorgijevska, N. (Author), Pike, S. (Author), Nybo, E., West Michigan Regional Undergraduate Science Research Conference (WMRUGS), "BioBricks® metabolic engineering of elloramycin and tetracenomycins," Van Andel Institute, Grand Rapids, MI, (November 5, 2020).