Associate Professor of Medicinal Chemistry
Pharmaceutical Science
Phone: (231) 591-2236
Email: [email protected]
Education
- PhD, University of Kentucky, College of Pharmacy, Pharmaceutical Sciences, Natural Products Biosynthesis
- BA, Transylvania University, Biology and Classics
Graduate/Post-Graduate Training
- Fellowship, Postdoctoral Fellowship, University of Kentucky College of Pharmacy, Lexington, KY
Biography
Dr. Nybo grew up in Knoxville, TN until he left for Lexington, KY where he completed his undergraduate and graduate studies. He graduated with a B.A. in Biology and Classics from Transylvania University in 2006. He went onto complete his Ph.D. in Pharmaceutical Sciences from the University of Kentucky in 2011.
He conducted a postdoctoral fellowship in the University of Kentucky Department of Plant and Soil Sciences from 2011-2014 in microbial biofuels research. In 2013, Dr. Nybo was invited back to Transylvania University as a Visiting Assistant Professor of General Chemistry.
Dr. Nybo joined the faculty of the College of Pharmacy, Department of Pharmaceutical Sciences in July 2014.
Publications and Intellectual Contributions
- Cited Research
Maki, K., Brown, K., Coe, M., Sohn, M., Nybo, E. (2019). "Design of experiments and metabolic engineering approach to enhance nogalamycin production in Streptomyces nogalater," bioRxiv. https://www.biorxiv.org/content/10.1101/804179v1 - Journal Article
Nybo, E., Lamberts, J. (2019). "Integrated use of LC/MS/MS and LC/QTOF/MS targeted metabolomics with automated label-free microscopy for quantification of purine metabolites in cultured mammalian cells," Purinergic Signaling. pp. 1-9. Rotterdam, Netherlands: Springer Netherlands. https://link.springer.com/article/10.1007%2Fs11302-018-9643-2#citeas - Book Chapter
Nybo, E., Kharel, M. K. (2018). "Recent developments in the quest for novel microbial natural products," Studies in Natural Products Chemistry. 59 Elsevier. https://www.elsevier.com/books/studies-in-natural-products-chemistry/atta-ur-rahman/978-0-444-64179-3 - Journal Article
Jiang, Z., Kempinski, C., Kumar, S., Kinison, S., Linscott, K., Nybo, E., Janse, S., Wood, C., Chappell, J. (2018). "Agronomic and chemical performance of field grown tobacco engineered for triterpene and methylated triterpene metabolism," Plant Biotechnology Journal. Wiley. - Journal Article
Saunders, J., Maki, K., Koski, R. R., Nybo, E. (2017). "Tavaborole, Efinaconazole, and Luliconazole: Three New Antimycotic Agents for Treatment of Dermatophytic Fungi," Journal of Pharmacy Practice. 30 (6). pp. 621-30. Brooklyn, NY: Sage Journals. - Journal Article
Nybo, E., McCormick, S. (2017). "Metabolic Engineering of Valerena-1,10-diene in Escherichia coli," Journal of Biotechnology. (262). pp. 60-66. Big Rapids: Elsevier. http://www.sciencedirect.com/science/article/pii/S0168165617316899 - Journal Article
Kumar, S., Kempinski, C., Zhuang, X., Norris, A., Mafu, S., Zi, J., Bell, S. A., Nybo, S. E., Kinison, S. E., Jiang, Z., Goklany, S., Linscott, K. B., Chen, X., Jia, Q., Brown, S. D., Bowman, J. L., Babbitt, P. C., Peters, R. J., Chen, F., Chappell, J. (2016). "Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha." The Plant cell. - Journal Article
Ricigliano, V., Kumar, S., Kinison, S., Brooks, C., Nybo, S. E., Chappell, J., Howarth, D. G. (2016). "Regulation of sesquiterpenoid metabolism in recombinant and elicited Valeriana officinalis hairy roots." Phytochemistry. - Journal Article
Nybo, E., Khan, N. E., Woolston, B. M., Curtis, W. R. (2015). "Metabolic engineering in chemolithoautotrophic hosts for the production of fuels and chemicals." Metabolic engineering. 30 pp. 105-20. - Journal Article
Khan, N. E., Nybo, S. E., Chappell, J., Curtis, W. R. (2015). "Triterpene hydrocarbon production engineered into a metabolically versatile host--Rhodobacter capsulatus." Biotechnology and bioengineering. 112 (8). pp. 1523-32.
Presentations
- Oral Presentation
Nybo, E., HatchEd 2019, "Genetic engineering: Making strides in the treatment of cancer," Ferris State University, Big Rapids, MI, (September 25, 2019). - Lecture
Nybo, E., ExamSoft Workshop, "Question Creation in ExamSoft," Ferris State University, College of Pharmacy, Big Rapids, MI, (August 21, 2019). - Poster
Nybo, E., Tran, J. (Author), West Michigan Regional Undergraduate Science Research Conference, "A BioBricks® Synthetic Biology Toolbox for Biosynthesis of Anthracyclinones," Van Andel Research Institute, Grand Rapids, MI, (November 10, 2018). - Poster
Nybo, E., Tran, J. (Author), American Society of Pharmacognosy Annual Meeting, "A BioBricks® Synthetic Biology Toolbox for Biosynthesis of Anthracyclinones," American Society of Pharmacognosy, Lexington, KY, (July 22, 2018). - Keynote/Plenary Address
Nybo, E., Ferris State University, College of Pharmacy Spring Seminar, "Jacoby Lecture- Synthetic life: making new medicines," Ferris State University, College of Pharmacy, Big Rapids, MI, (April 17, 2018). - Oral Presentation
Lamberts, J. (Presenter), Nybo, E. (Presenter), Professional Development Series, "ExamSoft Training Made Easy," Ferris State University College of Pharmacy, Big Rapids, MI, (August 8, 2017). - Poster
Nybo, E. (Author & Presenter), Sohn, M. (Author), Maki, K. (Author & Presenter), American Society of Pharmacognosy 2017 Annual Meeting, "Combined Use of Design-of-Experiments and Metabolic Engineering to Enhance Production of Nogalamycin," American Society of Pharmacognosy, Portland, OR, (July 31, 2017). - Poster
Nybo, E. (Author & Presenter), Tran, J. (Author), Lamberts, J. (Author), McCormick, S. (Author), American Society of Pharmacognosy Annual Meeting, "Progress in metabolic engineering production of valerenadiene," American Society of Pharmacognosy, Portland, OR, (July 30, 2017). - Poster
Tran, J. (Author & Presenter), Mccormick, S. P. (Author), Lamberts, J., Nybo, E. (Author), 253rd American Chemical Society National Meeting and Exposition, "Combinatorial engineering of the mevalonic acid pathway for optimization of valerena-1,10-diene production," American Chemical Society, San Francisco, California, (April 2, 2017). - Oral Presentation
Nybo, E., BK21 Lecture Series, "Metabolic Engineering of Valeriana Sesquiterpenes in Escherichia coli," Sunkyunkwan University, College of Pharmacy, Suwon, Korea, (August 2, 2016).