Tracey Boncher Ph.D.

Professor, Medicinal Chemistry
Office: PHR 309
Phone: (231) 591-2283
E-mail Address:
Lab: 231-591-7196 (212 Pharmacy)


  • Ph.D., Pharmaceutical Sciences: Medicinal Chemistry, Wayne State University, 2003
  • B.S., Biology/Chemistry, University of Michigan, 1998

Courses Taught:

PHAR 311: Medical Biochemistry
PHAR 411: Drug Action 1
PHAR 412: Drug Action 2
PHAR 413: Drug Action 3
PHAR 421: Infectious Diseases I
PHAR 422: Infectious Diseases II
PHAR 466: Medicinal Chemistry Research
PHAR 453: Topics in Nutritional Biochemistry

Research Interests:

The goal of the current research in my lab is to use solid phase synthesis to enhance and expand the synthesis and purification of novel Peroxisome Proliferator Activated Receptors (PPAR) gamma/delta dual agonists for the treatment of type II diabetes and Alzheimer’s Disease. 

Selected Publications:

  • Modern Chemistry and Applications, 2013, “Basic Concepts of Using Solid Phase Synthesis to Build Small Organic Molecules Using 2-Chlorotrityl Chloride Resin”, Bonkowski, Blake, Wieczorek, Jason, Patel, Mimansa, Craig, Chelsea, Gravelin, Alison, and Boncher, Tracey.
  • Bioorganic & Medicinal Chemistry Letters, 2013, 23(3):873-879. “Design, development and evaluation of novel dual PPAR gamma/delta agonists”, Symon Gathiaka, Gayani Nanayakkara, Tracey Boncher, Orlando Acevedo, Johnaton Wyble, Sagar Patel, Akash Patel, Mary Elizabeth Shane, Blake Bonkowski, Jason Wieczorek, Yinghui Rong, Kevin Huggins, Forest Smith, Rajesh H. Amin.
  • US Pharmacist, May 2012, 37(5): 39-42. “The Pharmacists role in Managing Pain Associated with Ocular Trauma”, Dinardo, A. and Boncher, T.
  • Essays in Biochemistry, The polyamines: Small Molecules in the Omics Era, Senanayake, T., Amunugama, H., Boncher, T.D., Casero, R.A., Woster, P.M., 26:77-94 2009
  • Essays in Biochemistry, 2009, 46:77-94. “Design of Polyamine-based Therapeutic Agents: New Targets and New Directions”, M.D. Thulani Senanayake, Hemali Amungama, Tracey D. Boncher, Robert A. Casero, and Patrick M. Woster.
  • Biochem Soc Trans, 2007, 35 (pt2) 356-63. “Polyamine-based Analogues as Biochemical Probes & Potential Therapeutics”, Boncher, T., Bi,X., Varghese, S., Casero, RA, Woster P.M.
  • Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine specific demethylase inhibitors,Pub.No:US 2007/0208082 A1, Boncher, T., Woster, P.M., Casero R.
  • Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors, 2005, US Patent WO/2007/02/839,PCTIUS2006/03/98. Woster, P.M., Ward, T.D., Casero, Jr R.A.
  • Cancer Chemotherapy & Pharmacology, 2003, 52(5)383-390. “Induction of the PAOh/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells”, Devereux W., Wang T, Stewart TM, Hacker A., Smith R., Frydman B., Valasinas AL, Reddy VK, Marton LJ, Ward TD, Woster PM, Casero RA.
  • Bioorganic & Medicinal Chemistry Letters, 2003, 13(10)1745-1749. “Piperazinyl-linked fluoroquinolone dimmers possessing potent antibacterial activity against drug-resistant strains of Staphylococcus aureus” Kerns, Robert, Rybak, Michael J., Kaatz, Glen W., Vaka Flamur, Cha, Raymond, Grucz, Richard G, Diwadkar, Veena U. and Ward, Tracey D.

Books Reviewed:

  • Basic Concepts in Medicinal Chemistry, American Society of Health System Pharmacists, 2013
  • Voet, Voet, Pratt Fundamentals of Biochemistry 4th edition, John Wiley & Sons Inc., 2013
  • Lehininger’s Principles of Biochemistry 6th edition, Freeman Publishing Co., 2012
  • Biochemistry for Pharmaceutical Sciences, Jones & Bartlett Learning, 2012
  • Remington: The Science & Practice of Pharmacy, “Integrated Principles of Medicinal Chemistry & Pharmacology” 22nd edition, 2011
  • Fundamentals of Biochemistry: Life at the Molecular Level, Voet, Voet, Pratt, 4th ed., 2011
  • Pharmaceutical Press, MCQs in Pharmaceutical Analysis, 2011
  • Review of Organic Functional Groups: Introduction to Medicinal Organic Chemistry 5th edition, Lippincott, Williams & Wilkins, 2008
  • American Society of Health-System Pharmacists, Proposed Medicinal Chemistry, Khan, Faruk, 2008
  • Review of Organic Chemistry for Pharmacy Students, Royal Pharmaceutical Society of Great Britain, 2007
  • Voet,Voet Biochemistry International Version,Wiley, 2007
  • Organic, Pharmaceutical and Medicinal Chemistry, Lippincott, Williams & Wilkins, 2006
  • Molecular Biology in Medicinal Chemistry, American Journal of Pharmaceutical Education, 2004
  • Molecular Biology in Medicinal Chemistry, John Wiley & Sons, 2003
  • Review of Organic Functional Groups, Lippincott Williams & Wilkins, 4th ed. 2003